The functional response of human monocyte-derived macrophages to serum amyloid A and Mycobacterium tuberculosis infection

The functional response of human monocyte-derived macrophages to serum amyloid A and Mycobacterium tuberculosis infection

IntroductionIn the course of tuberculosis (TB), the level of major acute phase protein, namely serum amyloid A (hSAA-1), increases up to a hundredfold in the pleural fluids of infected individuals. Tubercle bacilli infecting the human host can be opsonized by hSAA-1, which affects bacterial entry in...

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Main Authors: Malwina Kawka, Renata Płocińska, Przemysław Płociński, Jakub Pawełczyk, Marcin Słomka, Justyna Gatkowska, Katarzyna Dzitko, Bożena Dziadek, Jarosław Dziadek
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
human serum amyloid A
monocyte-derived macrophages
immunological response
host-pathogen transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1238132/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1238132/full

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