Establishment of a murine model of congenital toxoplasmosis and validation of a qPCR assay to assess the parasite load in maternal and fetal tissues

Toxoplasma gondii is the causative agent of toxoplasmosis, a disease that affects warm-blooded animals and one third of the human population worldwide. Pregnant women who have never been exposed to the parasite constitute an important risk group, as infection during pregnancy often leads to congenit...

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Bibliographic Details
Main Authors: Jéssica S. Souza, Priscila S. G. Farani, Beatriz I. S. Ferreira, Helene S. Barbosa, Rubem F. S. Menna-Barreto, Otacilio C. Moreira, Rafael M. Mariante
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1124378/full