Effects of One-Year Tofacitinib Therapy on Lipids and Adipokines in Association with Vascular Pathophysiology in Rheumatoid Arthritis

Effects of One-Year Tofacitinib Therapy on Lipids and Adipokines in Association with Vascular Pathophysiology in Rheumatoid Arthritis

Background: Cardiovascular (CV) morbidity, mortality and metabolic syndrome are associated with rheumatoid arthritis (RA). A recent trial has suggested increased risk of major CV events (MACE) upon the Janus kinase (JAK) inhibitor tofacitinib compared with anti-tumor necrosis factor α (TNF-α) therap...

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Bibliographic Details
Main Authors: Monika Czókolyová, Attila Hamar, Anita Pusztai, Gábor Tajti, Edit Végh, Zsófia Pethő, Nóra Bodnár, Ágnes Horváth, Boglárka Soós, Szilvia Szamosi, Anita Szentpéteri, Ildikó Seres, Mariann Harangi, György Paragh, György Kerekes, Levente Bodoki, Andrea Domján, Katalin Hodosi, Tamás Seres, György Panyi, Zoltán Szekanecz, Gabriella Szűcs
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomolecules
Subjects:
rheumatoid arthritis
tofacitinib
JAK inhibitors
lipids
adipokines
Online Access:https://www.mdpi.com/2218-273X/12/10/1483

Internet

https://www.mdpi.com/2218-273X/12/10/1483

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