A Rare <em>MSH2</em> Variant as a Candidate Marker for Lynch Syndrome II Screening in Tunisia: A Case of Diffuse Gastric Carcinoma

A Rare <em>MSH2</em> Variant as a Candidate Marker for Lynch Syndrome II Screening in Tunisia: A Case of Diffuse Gastric Carcinoma

Several syndromic forms of digestive cancers are known to predispose to early-onset gastric tumors such as Hereditary Diffuse Gastric Cancer (HDGC) and Lynch Syndrome (LS). LSII is an extracolonic cancer syndrome characterized by a tumor spectrum including gastric cancer (GC). In the current work, o...

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Bibliographic Details
Main Authors: Maria Kabbage, Jihenne Ben Aissa-Haj, Houcemeddine Othman, Amira Jaballah-Gabteni, Sarra Laarayedh, Sahar Elouej, Mouna Medhioub, Haifa Tounsi Kettiti, Amal Khsiba, Moufida Mahmoudi, Houda BelFekih, Afifa Maaloul, Hassen Touinsi, Lamine Hamzaoui, Emna Chelbi, Sonia Abdelhak, Mohamed Samir Boubaker, Mohamed Mousaddak Azzouz
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Genes
Subjects:
HDGC
<i>CDH1</i>-negative case
lynch syndrome II
genetic screening
target gene sequencing
DNA repair genes
Online Access:https://www.mdpi.com/2073-4425/13/8/1355

Internet

https://www.mdpi.com/2073-4425/13/8/1355

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