Facile adipocyte uptake and liver/adipose tissue delivery of conjugated linoleic acid-loaded tocol nanocarriers for a synergistic anti-adipogenesis effect

Facile adipocyte uptake and liver/adipose tissue delivery of conjugated linoleic acid-loaded tocol nanocarriers for a synergistic anti-adipogenesis effect

Abstract Obesity is a major risk to human health. Adipogenesis is blocked by α-tocopherol and conjugated linoleic acid (CLA). However, their effect at preventing obesity is uncertain. The effectiveness of the bioactive agents is associated with their delivery method. Herein, we designed CLA-loaded t...

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Bibliographic Details
Main Authors: Ching-Yun Hsu, Chia-Chih Liao, Zih-Chan Lin, Ahmed Alalaiwe, Erica Hwang, Tzu-Wei Lin, Jia-You Fang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Nanobiotechnology
Subjects:
Conjugated linoleic acid
α-tocopherol
Nanostructured lipid carriers
Passive targeting
Anti-adipogenesis
Obesity
Online Access:https://doi.org/10.1186/s12951-024-02316-8

Internet

https://doi.org/10.1186/s12951-024-02316-8

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