Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound

Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound

Infection is a major co-morbidity that contributes to impaired healing in diabetic wounds. Although impairments in diabetic neutrophils have been blamed for this co-morbidity, what causes these impairments and whether they can be overcome, remain largely unclear. Diabetic neutrophils, isolated from...

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Bibliographic Details
Main Authors: Ruchi Roy, Janet Zayas, Sunil K Singh, Kaylee Delgado, Stephen J Wood, Mohamed F Mohamed, Dulce M Frausto, Yasmeen A Albalawi, Thea P Price, Ricardo Estupinian, Eileena F Giurini, Timothy M Kuzel, Andrew Zloza, Jochen Reiser, Sasha H Shafikhani
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
Pseudomonas aeruginosa
wound healing
innate immunity
neutrophils
diabetes
chemotactic response
Online Access:https://elifesciences.org/articles/72071

Internet

https://elifesciences.org/articles/72071

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