Gamma-tubulin is required for bipolar spindle assembly and for proper kinetochore microtubule attachments during prometaphase I in Drosophila oocytes.

In many animal species the meiosis I spindle in oocytes is anastral and lacks centrosomes. Previous studies of Drosophila oocytes failed to detect the native form of the germline-specific γ-tubulin (γTub37C) in meiosis I spindles, and genetic studies have yielded conflicting data regarding the role...

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Bibliographic Details
Main Authors: Stacie E Hughes, J Scott Beeler, Angela Seat, Brian D Slaughter, Jay R Unruh, Elisabeth Bauerly, Heinrich J G Matthies, R Scott Hawley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3154956?pdf=render