Subthalamic nucleus deep brain stimulation driven by primary motor cortex γ2 activity in parkinsonian monkeys

Abstract In parkinsonism, subthalamic nucleus (STN) electrical deep brain stimulation (DBS) improves symptoms, but may be associated with side effects. Adaptive DBS (aDBS), which enables modulation of stimulation, may limit side effects, but limited information is available about clinical effectiven...

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Bibliographic Details
Main Authors: Olivier Darbin, Nobuhiko Hatanaka, Sayuki Takara, Nobuya Kaneko, Satomi Chiken, Dean Naritoku, Anthony Martino, Atsushi Nambu
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10130-1