ANTIARRHYTHMIC ACTIVITY MONOGAMISTIC AMIDES AND HYDRAZIDES 1,4-DICARBOXYLIC ACIDS

The antiarrhythmic activity of 19 derivatives 1,4-dicarboxylic acids in experiments on white mice on the model of chlorocalcium arrhythmia and acute toxicity of 6 compounds. As a standard, the drug «Lidocaine» was used. Two compounds showed an antiarrhythmic effect exceeding the standard effect by 6...

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Bibliographic Details
Main Authors: N. V. Kolotova, I. P. Rudakova
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/592