Next‐generation sequencing reveals the presence of DDX41 mutations in acute lymphoblastic leukemia and aplastic anemia

Next‐generation sequencing reveals the presence of DDX41 mutations in acute lymphoblastic leukemia and aplastic anemia

Abstract Limited studies have been described DEAD‐box helicase 41 (DDX41) mutations in hematological diseases other than myeloid neoplasms. In this study, DDX41 mutations were identified in 0.8% of myeloid neoplasms, 0.9% of acute lymphoblastic leukemia (ALL), and 1.0% of aplastic anemia (AA). A tot...

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Bibliographic Details
Main Authors: Yang Zhang, Fang Wang, Xue Chen, Hong Liu, Xiaoliang Wang, Jiaqi Chen, Panxiang Cao, Xiaoli Ma, Hongxing Liu
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:eJHaem
Subjects:
acute lymphoblastic leukemia
aplastic anemia
DDX41 mutations
genetic predisposition
Online Access:https://doi.org/10.1002/jha2.256

Internet

https://doi.org/10.1002/jha2.256

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