A label-free and ratiometric fluorescent immunosensor by integrating CRISPR/Cas 12a and 3D DNA nanomachine
Sensitive, selective, especially label-free detection of disease relevant protein biomarkers is highly valuable for clinical diagnosis and disease process monitoring but remains a challenge. Herein, with prostate specific antigen (PSA) as a model target, we have designed a label-free ratiometric flu...
Autores principales: | , , , , , , , |
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Formato: | Artículo |
Lenguaje: | English |
Publicado: |
Elsevier
2023-08-01
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Colección: | Talanta Open |
Acceso en línea: | http://www.sciencedirect.com/science/article/pii/S2666831923000310 |