Characterization of the Effect of <i>N</i>-(2-Methoxyphenyl)-1-methyl-1<i>H</i>-benzimidazol-2-amine, Compound 8, against <i>Leishmania mexicana</i> and Its In Vivo Leishmanicidal Activity

Characterization of the Effect of <i>N</i>-(2-Methoxyphenyl)-1-methyl-1<i>H</i>-benzimidazol-2-amine, Compound 8, against <i>Leishmania mexicana</i> and Its In Vivo Leishmanicidal Activity

Chemotherapy currently available for leishmaniasis treatment has many adverse side effects and drug resistance. Therefore, the identification of new targets and the development of new drugs are urgently needed. Previously, we reported the synthesis of a <i>N</i>-(2-methoxyphenyl)-1-methy...

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Bibliographic Details
Main Authors: Rocío Nieto-Meneses, Rafael Castillo, Alicia Hernández-Campos, Benjamín Nogueda-Torres, Edgar Oliver López-Villegas, Adriana Moreno-Rodríguez, Félix Matadamas-Martínez, Lilián Yépez-Mulia
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
leishmanicidal activity
benzimidazole derivative
ultrastructural studies
ROS production
in vivo activity
Online Access:https://www.mdpi.com/1422-0067/25/1/659

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https://www.mdpi.com/1422-0067/25/1/659

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