Rare KCNQ4 variants found in public databases underlie impaired channel activity that may contribute to hearing impairment

Rare KCNQ4 variants found in public databases underlie impaired channel activity that may contribute to hearing impairment

Deafness: Missed mutations raise risk of hearing loss A gene associated with hereditary hearing loss may play a greater role than previously recognized in age-related auditory impairment. Many cases of autosomal dominant non-syndromic hearing loss (ADNSHL) arise from defects in KCNQ4, a protein that...

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Bibliographic Details
Main Authors: Jinsei Jung, Haiyue Lin, Young Ik Koh, Kunhi Ryu, Joon Suk Lee, John Hoon Rim, Hye Ji Choi, Hak Joon Lee, Hye-Youn Kim, Seyoung Yu, Hyunsoo Jin, Ji Hyun Lee, Min Goo Lee, Wan Namkung, Jae Young Choi, Heon Yung Gee
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0300-9

Internet

https://doi.org/10.1038/s12276-019-0300-9

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