Pharmacokinetics and Dosing Regimens of Direct Oral Anticoagulants in Morbidly Obese Patients: An Updated Literature Review

Pharmacokinetics and Dosing Regimens of Direct Oral Anticoagulants in Morbidly Obese Patients: An Updated Literature Review

Data on the impact of morbid obesity (body mass index [BMI] ≥ 40 kg/m 2 ) on the pharmacokinetics (PK), pharmacodynamics (PD) of direct oral anticoagulants (DOACs) are relatively limited, making it difficult to design optimal dosing regimens in morbidly obese patients. To review literature on PK/PD...

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Bibliographic Details
Main Authors: Ying Zhao MS, Mingxing Guo MS, Dandan Li MS, Wanyi Xu MS, Chen Pan MS, Chaoran He MS, Xiangli Cui PhD
Format: Article
Language:English
Published: SAGE Publishing 2023-02-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296231153638

Internet

https://doi.org/10.1177/10760296231153638

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