An RNA Triangle with Six Ribozyme Units Can Promote a <i>Trans</i>-Splicing Reaction through Trimerization of Unit Ribozyme Dimers

An RNA Triangle with Six Ribozyme Units Can Promote a <i>Trans</i>-Splicing Reaction through Trimerization of Unit Ribozyme Dimers

Ribozymes are catalytic RNAs that are attractive platforms for the construction of nanoscale objects with biological functions. We designed a dimeric form of the <i>Tetrahymena</i> group I ribozyme as a unit structure in which two ribozymes were connected in a tail-to-tail manner with a...

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Bibliographic Details
Main Authors: Junya Akagi, Takahiro Yamada, Kumi Hidaka, Yoshihiko Fujita, Hirohide Saito, Hiroshi Sugiyama, Masayuki Endo, Shigeyoshi Matsumura, Yoshiya Ikawa
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Applied Sciences
Subjects:
catalytic RNA
group I ribozyme
RNA nanostructure
RNA nanotechnology
RNA-protein complex
<i>trans</i>-splicing
Online Access:https://www.mdpi.com/2076-3417/11/6/2583

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https://www.mdpi.com/2076-3417/11/6/2583

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