Cimicifugae Rhizoma Extract Attenuates Oxidative Stress and Airway Inflammation via the Upregulation of Nrf2/HO-1/NQO1 and Downregulation of NF-κB Phosphorylation in Ovalbumin-Induced Asthma

Cimicifugae Rhizoma Extract Attenuates Oxidative Stress and Airway Inflammation via the Upregulation of Nrf2/HO-1/NQO1 and Downregulation of NF-κB Phosphorylation in Ovalbumin-Induced Asthma

Cimicifugae Rhizoma has been used as a medicinal herb for fever, pain, and inflammation in East Asia. We conducted this study because the effect of Cimicifugae Rhizoma extract (CRE) on allergic asthma has not yet been evaluated. To induce allergic airway inflammation, we intraperitoneally injected o...

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Bibliographic Details
Main Authors: Je-Oh Lim, Kwang Hoon Song, Ik Soo Lee, Se-Jin Lee, Woong-Il Kim, So-Won Pak, In-Sik Shin, Taesoo Kim
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Antioxidants
Subjects:
Cimicifugae Rhizoma
asthma
nuclear factor erythroid 2-related factor 2 (Nrf2)
heme oxygenase-1 (HO-1)
nuclear factor-κB (NF-κB)
matrix metalloproteinase-9 (MMP-9)
Online Access:https://www.mdpi.com/2076-3921/10/10/1626

Internet

https://www.mdpi.com/2076-3921/10/10/1626

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