AD−1 Small Molecule Improves Learning and Memory Function in Scopolamine-Induced Amnesic Mice Model through Regulation of CREB/BDNF and NF-κB/MAPK Signaling Pathway

AD−1 Small Molecule Improves Learning and Memory Function in Scopolamine-Induced Amnesic Mice Model through Regulation of CREB/BDNF and NF-κB/MAPK Signaling Pathway

Cognitive decline and memory impairment induced by oxidative brain damage are the critical pathological hallmarks of Alzheimer’s disease (AD). Based on the potential neuroprotective effects of AD−1 small molecule, we here explored the possible underlying mechanisms of the protective effect of AD-1 s...

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Bibliographic Details
Main Authors: Rengasamy Balakrishnan, Ju-Young Park, Duk-Yeon Cho, Jae-Yong Ahn, Dong-Sun Yoo, Sang-Ho Seol, Sung-Hwa Yoon, Dong-Kug Choi
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Antioxidants
Subjects:
AD−1 small molecule
scopolamine
oxidative stress
memory impairment
neuroinflammation
apoptosis
Online Access:https://www.mdpi.com/2076-3921/12/3/648

Internet

https://www.mdpi.com/2076-3921/12/3/648

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