Comprehensive analysis of a necroptosis-associated diagnostic signature for myelodysplastic syndromes based on single-cell RNA-seq and bulk RNA-seq

Comprehensive analysis of a necroptosis-associated diagnostic signature for myelodysplastic syndromes based on single-cell RNA-seq and bulk RNA-seq

Abstract Background Myelodysplastic syndromes (MDS) are heterogeneous and clonal hematological disorders. The role and mechanism of necroptosis in MDS remain poorly understood. Methods mRNA expression profiles and single-cell RNA-sequencing (scRNA-seq) data were sourced from the GEO database. ScRNA-...

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Bibliographic Details
Main Authors: Huimin Zhang, Li Zhang, Xiaoning Liang, Lihong Zhang, Bing Ma, Yuexian Li, Jianying Wang, Yang Shen, Yuhui Pang, Jianjun Xiong
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Hereditas
Subjects:
Myelodysplastic syndromes
Necroptosis
Immune cell infiltration
Prognosis
Online Access:https://doi.org/10.1186/s41065-024-00335-x

Internet

https://doi.org/10.1186/s41065-024-00335-x

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