Escherichia coli Promotes Endothelial to Mesenchymal Transformation of Liver Sinusoidal Endothelial Cells and Exacerbates Nonalcoholic Fatty Liver Disease Via Its FlagellinSummary

Escherichia coli Promotes Endothelial to Mesenchymal Transformation of Liver Sinusoidal Endothelial Cells and Exacerbates Nonalcoholic Fatty Liver Disease Via Its FlagellinSummary

Background＆Aims: Gut bacteria translocate into the liver through a disrupted gut vascular barrier, which is an early and common event in the development of nonalcoholic fatty liver disease (NAFLD). Liver sinusoidal endothelial cells (LSECs) are directly exposed to translocated gut microbiota in port...

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Bibliographic Details
Main Authors: Bo Shen, Tianyi Gu, Zhenyang Shen, Cui Zhou, Yuecheng Guo, Junjun Wang, Binghang Li, Xianjun Xu, Fei Li, Qidi Zhang, Xiaobo Cai, Hui Dong, Lungen Lu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Escherichia coli
Flagellin
Liver Sinusoidal Endothelial Cells
Endothelial to Mesenchymal Transformation
Nonalcoholic Fatty Liver Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X23001467

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http://www.sciencedirect.com/science/article/pii/S2352345X23001467

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