Pathological Studies on Hantaan Virus-Infected Mice Simulating Severe Hemorrhagic Fever with Renal Syndrome

Pathological Studies on Hantaan Virus-Infected Mice Simulating Severe Hemorrhagic Fever with Renal Syndrome

Hantaan virus is the causative agent of hemorrhagic fever with renal syndrome (HFRS). The Hantaan virus strain, Korean hemorrhagic fever virus clone-5 (KHF5), causes weight loss and renal hemorrhage in laboratory mice. Clone-4 (KHF4), which has a single E417K amino acid change in its glycoprotein, i...

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Bibliographic Details
Main Authors: Zhouoxing Wei, Kenta Shimizu, Rakiiya S. Sarii, Devinda S. Muthusinghe, Sithumini M. W. Lokupathirage, Junko Nio-Kobayashi, Kumiko Yoshimatsu
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
Hantaan virus
virulence
mouse model
renal function
neutrophil activation
Online Access:https://www.mdpi.com/1999-4915/14/10/2247

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https://www.mdpi.com/1999-4915/14/10/2247

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