Deformation Microscopy for Dynamic Intracellular and Intranuclear Mapping of Mechanics with High Spatiotemporal Resolution

Summary: Structural heterogeneity is a hallmark of living cells that drives local mechanical properties and dynamic cellular responses. However, the robust quantification of intracellular mechanics is lacking from conventional methods. Here, we describe the development of deformation microscopy, whi...

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Bibliographic Details
Main Authors: Soham Ghosh, Benjamin Seelbinder, Jonathan T. Henderson, Ryan D. Watts, Adrienne K. Scott, Alexander I. Veress, Corey P. Neu
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719304644