Primary cilia control cellular patterning of Meibomian glands during morphogenesis but not lipid composition

Meibomian gland (MG) cells are ciliated in early stages of development and primary cilium is required to regulate early MG cell patterning within developing glands, with cilia-mediated signaling pathways identified as therapeutic targets.

Bibliographic Details
Main Authors: Céline Portal, Yvonne Lin, Varuni Rastogi, Cornelia Peterson, Samuel Chi-Hung Yiu, James W. Foster, Amber Wilkerson, Igor A. Butovich, Carlo Iomini
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04632-5