From genomes to vaccines via the proteome

An effective vaccine against schistosomiasis mansoni would be a valuable control tool and the high levels of protection elicited in rodents and primates by radiation-attenuated cercariae provide proof of principle. A major obstacle to vaccine development is the difficulty of identifying the antigens...

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Bibliographic Details
Main Authors: R Alan Wilson, Rachel S Curwen, Simon Braschi, Stephanie L Hall, Patricia S Coulson, Peter D Ashton
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2004-08-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000900008