Design and Optimization of Orally Administered Luteolin Nanoethosomes to Enhance Its Anti-Tumor Activity against Hepatocellular Carcinoma

Design and Optimization of Orally Administered Luteolin Nanoethosomes to Enhance Its Anti-Tumor Activity against Hepatocellular Carcinoma

Luteolin (LUT) is a natural flavonoid with low oral bioavailability with restricted clinical applications due to its low solubility. LUT shows significant anti-tumor activity in many cancer cells, including hepatocellular carcinoma (HCC). The most recent trend in pharmaceutical innovations is the ap...

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Bibliographic Details
Main Authors: Mahmoud M. A. Elsayed, Tarek M. Okda, Gamal M. K. Atwa, Gamal A. Omran, Atef E. Abd Elbaky, Abd El hakim Ramadan
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
luteolin
ethosomes
nano-sized vesicles
nanoparticle
hepatocellular carcinoma
oxidative stress biomarkers
Online Access:https://www.mdpi.com/1999-4923/13/5/648

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https://www.mdpi.com/1999-4923/13/5/648

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