Down-regulation of circ_0058058 suppresses proliferation, angiogenesis and metastasis in multiple myeloma through miR-338-3p/ATG14 pathway

Down-regulation of circ_0058058 suppresses proliferation, angiogenesis and metastasis in multiple myeloma through miR-338-3p/ATG14 pathway

Abstract Background Multiple myeloma (MM) is one of the most frequently diagnosed hematological malignancy. Dysregulation of circular RNAs (circRNAs) has important impacts on MM process. Herein, this work aimed to investigate the role and mechanism of circ_0058058 in MM progression. Methods Levels o...

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Bibliographic Details
Main Authors: Lianguo Xue, Tao Jia, Yuanxin Zhu, Lidong Zhao, Jianping Mao
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
circ_0058058
miR-338-3p
ATG14
Apoptosis
Metastasis
Multiple myeloma
Online Access:https://doi.org/10.1186/s13018-021-02867-8

Internet

https://doi.org/10.1186/s13018-021-02867-8

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