Calcium bursts allow rapid reorganization of EFhD2/Swip-1 cross-linked actin networks in epithelial wound closure

Calcium bursts allow rapid reorganization of EFhD2/Swip-1 cross-linked actin networks in epithelial wound closure

Calcium serves as an important second messenger in signal transduction to the actin cytoskeleton. Here, we identify EFhD2/Swip-1 as a calcium-dependent actin cross-linker promoting rapid reorganization of actin networks in epithelial wound closure.

Bibliographic Details
Main Authors: Franziska Lehne, Thomas Pokrant, Sabnam Parbin, Gabriela Salinas, Jörg Großhans, Katja Rust, Jan Faix, Sven Bogdan
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30167-0

Internet

https://doi.org/10.1038/s41467-022-30167-0

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