Outcomes of allogeneic haematopoietic stem cell transplantation for paediatric patients with MLL-rearranged acute myeloid leukaemia

Outcomes of allogeneic haematopoietic stem cell transplantation for paediatric patients with MLL-rearranged acute myeloid leukaemia

Abstract Background The presence of mixed-lineage leukaemia rearrangement (MLL-r) in paediatric patients with acute myeloid leukaemia (AML) is a poor prognostic predictor. Whether allogeneic haematopoietic stem cell transplantation (allo-HSCT) is beneficial in such cases remains unclear. Methods We...

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Bibliographic Details
Main Authors: Lu Bai, Yong-zhan Zhang, Chen-hua Yan, Yu Wang, Lan-ping Xu, Xiao-hui Zhang, Le-ping Zhang, Xiao-jun Huang, Yi-fei Cheng
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Cancer
Subjects:
MLL rearrangement
Paediatric patient
Acute myeloid leukaemia
Haploidentical haematopoietic stem cell transplantation
Online Access:https://doi.org/10.1186/s12885-022-09978-3

Internet

https://doi.org/10.1186/s12885-022-09978-3

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