Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation
<p>Abstract</p> <p>Background</p> <p>Previously we reported 1 μM synthetic human amyloid beta<sub>1-42 </sub>oligomers induced cofilin dephosphorylation (activation) and formation of cofilin-actin rods within rat hippocampal neurons primarily localized to th...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-01-01
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Series: | Molecular Neurodegeneration |
Online Access: | http://www.molecularneurodegeneration.com/content/6/1/10 |