Animal models of congenital zika syndrome provide mechanistic insight into viral pathogenesis during pregnancy.

In utero Zika virus (ZIKV; family Flaviviridae) infection causes a distinct pattern of birth defects and disabilities in the developing fetus and neonate that has been termed congenital zika syndrome (CZS). Over 8,000 children were affected by the 2016 to 2017 ZIKV outbreak in the Americas, many of...

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Bibliographic Details
Main Authors: Harish Narasimhan, Anna Chudnovets, Irina Burd, Andrew Pekosz, Sabra L Klein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008707