Pharmacokinetic analysis of new synthetic antimalarial N-251

Pharmacokinetic analysis of new synthetic antimalarial N-251

Abstract Background With the emergence and growing number of drug-resistant Plasmodium falciparum, a new drug for malaria control must be urgently developed. The new antimalarial synthetic compound N-251 was recently discovered. As an endoperoxide structure in the body, the compound shows high antim...

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Bibliographic Details
Main Authors: Kazuaki Okada, Akira Sato, Akiko Hiramoto, Rena Isogawa, Yuji Kurosaki, Kazutaka Higaki, Shin-Ichi Miyoshi, Kyung-Soo Chang, Hye-Sook Kim
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Tropical Medicine and Health
Subjects:
Synthetic endoperoxide
6-(1,2,6,7-tetraoxaspiro [7.11] nonadec-4-yl)hexan-1-ol (N-251)
Pharmacokinetic (PK) study
Bioavailability (F)
Antimalarial medicine
Online Access:http://link.springer.com/article/10.1186/s41182-019-0167-4

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http://link.springer.com/article/10.1186/s41182-019-0167-4

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