SIRT7 and p53 interaction in embryonic development and tumorigenesis

SIRT7 and p53 interaction in embryonic development and tumorigenesis

p53 is a hallmark tumor suppressor due in part to its role in cell cycle progression, DNA damage repair, and cellular apoptosis; its protein activity interrelates with the Sirtuin family of proteins, major regulators of the cellular response to metabolic, oxidative, and genotoxic stress. In the rece...

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Bibliographic Details
Main Authors: Berta N. Vazquez, Irene Fernández-Duran, Yurdiana Hernandez, Shahriar Tarighi, Joshua K. Thackray, Maria Espinosa-Alcantud, Poonam Kumari, Alessandro Ianni, Lionel Cesaire, Thomas Braun, Manel Esteller, Jay Tischfield, Alejandro Vaquero, Lourdes Serrano
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
p53
SIRTUIN
Sirt7
embryonic development
tumor suppressor
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1281730/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1281730/full

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