Myo-Inositol Levels in the Dorsal Hippocampus Serve as Glial Prognostic Marker of Mild Cognitive Impairment in Mice

Myo-Inositol Levels in the Dorsal Hippocampus Serve as Glial Prognostic Marker of Mild Cognitive Impairment in Mice

Dementia is a devastating age-related disorder. Its therapy would largely benefit from the identification of susceptible subjects at early, prodromal stages of the disease. To search for such prognostic markers of cognitive impairment, we studied spatial navigation in male BALBc vs. B6N mice in comb...

Full description

Bibliographic Details
Main Authors: Tim Ebert, Daniel E. Heinz, Suellen Almeida-Corrêa, Renata Cruz, Frederik Dethloff, Tibor Stark, Thomas Bajaj, Oriana M. Maurel, Fabiola M. Ribeiro, Silvio Calcagnini, Kathrin Hafner, Nils C. Gassen, Christoph W. Turck, Benoit Boulat, Michael Czisch, Carsten T. Wotjak
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
spatial memory
biomarker
MRS
MCI
glia
astrocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.731603/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.731603/full

Similar Items