Aspirin/amoxicillin loaded chitosan microparticles and polydopamine modified titanium implants to combat infections and promote osteogenesis

Abstract It is known that titanium (Ti) implant surfaces exhibit poor antibacterial properties and osteogenesis. In this study, chitosan particles loaded with aspirin, amoxicillin or aspirin + amoxicillin were synthesized and coated onto implant surfaces. In addition to analysing the surface charact...

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Bibliographic Details
Main Authors: Yun Shi, Yongzhen Lai, Yan Guo, Zhiyu Cai, Chuanqing Mao, Meng Lu, Chengyan Ren, Joo L. Ong, Weihui Chen
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-57156-1