Increased Alzheimer's risk during the menopause transition: A 3-year longitudinal brain imaging study.

Two thirds of all persons with late-onset Alzheimer's disease (AD) are women. Identification of sex-based molecular mechanisms underpinning the female-based prevalence of AD would advance development of therapeutic targets during the prodromal AD phase when prevention or delay in progression is...

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Bibliographic Details
Main Authors: Lisa Mosconi, Aneela Rahman, Ivan Diaz, Xian Wu, Olivia Scheyer, Hollie Webb Hristov, Shankar Vallabhajosula, Richard S Isaacson, Mony J de Leon, Roberta Diaz Brinton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0207885