Hepatic toxicity caused by PLGA-microspheres containing usnic acid from the lichen C ladonia substellata (AHTI) during pregnancy in Wistar rats
ABSTRACT This study aimed to evaluate the teratogenic and hepatotoxic potential of the usnic acid encapsulated into PLGA-microspheres. In total, 12 female Wistar rats in pregnancy were randomly distributed in the control group (n= 6) that received 1.0 mL of physiological solution and treatment group...
Main Authors: | KETSIA S.N. MARINHO, ERIVALDO A. ANTONIO, CAMILLA V.N.S. SILVA, KEILA T. DA SILVA, VALÉRIA W. TEIXEIRA, FRANCISCO C.A. DE AGUIAR JUNIOR, KATHARINE R.P. DOS SANTOS, NICÁCIO H. DA SILVA, NOEMIA P.S. SANTOS |
---|---|
Format: | Article |
Language: | English |
Published: |
Academia Brasileira de Ciências
|
Series: | Anais da Academia Brasileira de Ciências |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000301073&lng=en&tlng=en |
Similar Items
-
Bioproduction of usnic acid from acetate by kaolinite immobilized cells of Cladonia substellata Vain.
by: Eugenia C. Pereira, et al.
Published: (2014-01-01) -
Planned Pregnancy in Kidney Transplantation. A Calculated Risk
by: Claudio Ponticelli, et al.
Published: (2021-09-01) -
Inoffensivity of imupurin in pregnancy
by: Ina Pogonea, et al.
Published: (2019-03-01) -
Dataset on usnic acid from Cladonia substellata Vainio (Lichen) schistosomiasis mansoni's vector control and environmental toxicity
by: Hallysson Douglas Andrade de Araújo, et al.
Published: (2018-04-01) -
Fetotoxicity of Nanoparticles: Causes and Mechanisms
by: Chuanfeng Teng, et al.
Published: (2021-03-01)