Dopamine D<sub>2</sub> and Serotonin 5-HT<sub>1A</sub> Dimeric Receptor-Binding Monomeric Antibody scFv as a Potential Ligand for Carrying Drugs Targeting Selected Areas of the Brain

Dopamine D<sub>2</sub> and Serotonin 5-HT<sub>1A</sub> Dimeric Receptor-Binding Monomeric Antibody scFv as a Potential Ligand for Carrying Drugs Targeting Selected Areas of the Brain

Targeted therapy uses multiple ways of ensuring that the drug will be delivered to the desired site. One of these ways is an encapsulation of the drug and functionalization of the surface. Among the many molecules that can perform such a task, the present work focused on the antibodies of single-cha...

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Bibliographic Details
Main Authors: Agata Kowalik, Mateusz Majerek, Krzysztof Mrowiec, Joanna Solich, Agata Faron-Górecka, Olga Woźnicka, Marta Dziedzicka-Wasylewska, Sylwia Łukasiewicz
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
scFv antibody
D<sub>2</sub>–5-HT<sub>1A</sub> heteromer
nanoparticles
nanomedicine
targeted drug delivery
nanogold particles
Online Access:https://www.mdpi.com/2218-273X/12/6/749

Internet

https://www.mdpi.com/2218-273X/12/6/749

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