Every Beat You Take—The Wilms′ Tumor Suppressor WT1 and the Heart

Every Beat You Take—The Wilms′ Tumor Suppressor WT1 and the Heart

Nearly three decades ago, the Wilms’ tumor suppressor Wt1 was identified as a crucial regulator of heart development. Wt1 is a zinc finger transcription factor with multiple biological functions, implicated in the development of several organ systems, among them cardiovascular structures. This revie...

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Bibliographic Details
Main Authors: Nicole Wagner, Kay-Dietrich Wagner
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
Wilms’ tumor suppressor 1 (Wt1)
heart
cardiac development
coronary vessel formation
transcriptional regulation
cardiac malformation
Online Access:https://www.mdpi.com/1422-0067/22/14/7675

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https://www.mdpi.com/1422-0067/22/14/7675

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