Role of Receptor Profiling for Personalized Therapy in a Patient with a Growth Hormone-Secreting Macroadenoma Resistant to First-Generation Somatostatin Analogues

Role of Receptor Profiling for Personalized Therapy in a Patient with a Growth Hormone-Secreting Macroadenoma Resistant to First-Generation Somatostatin Analogues

Background: Acromegaly is almost always caused by a pituitary adenoma and is associated with high morbidity and mortality when uncontrolled. Trans-sphenoidal removal of the adenoma is the mainstay of therapy, but fails to control the disease in a significant number of patients who require further tr...

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Bibliographic Details
Main Authors: Krystallenia I. Alexandraki, Eirini Papadimitriou, Vasiliki Mavroeidi, Georgios Kyriakopoulos, Antonios Xydakis, Theodoros G. Papaioannou, Denise Kolomodi, Gregory A. Kaltsas, Ashley B. Grossman
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Journal of Personalized Medicine
Subjects:
acromegaly
personalized treatment
somatostatin receptor
e-cadherin
resistant acromegaly
somatostatin analogue
Online Access:https://www.mdpi.com/2075-4426/9/4/48

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https://www.mdpi.com/2075-4426/9/4/48

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