Exosomes derived from bone marrow mesenchymal stem cell preconditioned by low-intensity pulsed ultrasound stimulation promote bone–tendon interface fibrocartilage regeneration and ameliorate rotator cuff fatty infiltration

Background: Fibrovascular scar healing of bone-tendon interface (BTI) instead of functional fibrocartilage regeneration is the main concern associated with unsatisfactory prognosis in rotator cuff repair. Mesenchymal stem cells (MSCs) exosomes have been reported to be a new promising cell-free appro...

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Bibliographic Details
Main Authors: Bing Wu, Tao Zhang, Huabin Chen, Xin Shi, Changbiao Guan, Jianzhong Hu, Hongbin Lu
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X24000822