A Systematic Review of Oxidative Stress and Safety of Antioxidants in Diabetes: Focus on Islets and Their Defense

A growing body of evidence suggests that hyperglycemia-induced oxidative stress plays an important role in diabetic complications, especially β-cell dysfunction and failure. Under physiological conditions, reactive oxygen species serve as second messengers that facilitate signal transduction and gen...

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Bibliographic Details
Main Authors: Udayakumar Karunakaran, Keun-Gyu Park
Format: Article
Language:English
Published: Korean Diabetes Association 2013-04-01
Series:Diabetes & Metabolism Journal
Subjects:
Online Access:http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-37-106.pdf