Graphene Substrates Promote the Differentiation of Inner Ear Lgr5+ Progenitor Cells Into Hair Cells

Graphene Substrates Promote the Differentiation of Inner Ear Lgr5+ Progenitor Cells Into Hair Cells

The ideal treatment for sensory hearing loss is to regenerate inner ear hair cells (HCs) through stem cell therapy, thereby restoring the function and structure of the cochlea. Previous studies have found that Lgr5+ supporting cells (SCs) in the inner ear can regenerate HCs, thus being considered in...

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Bibliographic Details
Main Authors: Xiaoqiong Ding, Yangnan Hu, Hong Cheng, Xiaoli Zhang, Ling Lu, Song Gao, Cheng Cheng, Lifen Wang, Xiaoyun Qian, Chen Zhang, Renjie Chai, Xia Gao, Zhichun Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
graphene
sensorineural hearing loss
hair cell regeneration
proliferation
differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.927248/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.927248/full

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