cAMP level modulates scleral collagen remodeling, a critical step in the development of myopia.

The development of myopia is associated with decreased ocular scleral collagen synthesis in humans and animal models. Collagen synthesis is, in part, under the influence of cyclic adenosine monophosphate (cAMP). We investigated the associations between cAMP, myopia development in guinea pigs, and co...

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Main Authors: Yijin Tao, Miaozhen Pan, Shufeng Liu, Fang Fang, Runxia Lu, Chanyi Lu, Min Zheng, Jianhong An, Hongjia Xu, Fuxin Zhao, Jiang-Fan Chen, Jia Qu, Xiangtian Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3741144?pdf=render