Reconciling functional differences in populations of neurons recorded with two-photon imaging and electrophysiology

Reconciling functional differences in populations of neurons recorded with two-photon imaging and electrophysiology

Extracellular electrophysiology and two-photon calcium imaging are widely used methods for measuring physiological activity with single-cell resolution across large populations of cortical neurons. While each of these two modalities has distinct advantages and disadvantages, neither provides complet...

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Bibliographic Details
Main Authors: Joshua H Siegle, Peter Ledochowitsch, Xiaoxuan Jia, Daniel J Millman, Gabriel K Ocker, Shiella Caldejon, Linzy Casal, Andy Cho, Daniel J Denman, Séverine Durand, Peter A Groblewski, Gregg Heller, India Kato, Sara Kivikas, Jérôme Lecoq, Chelsea Nayan, Kiet Ngo, Philip R Nicovich, Kat North, Tamina K Ramirez, Jackie Swapp, Xana Waughman, Ali Williford, Shawn R Olsen, Christof Koch, Michael A Buice, Saskia EJ de Vries
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
extracellular electrophysiology
calcium imaging
in vivo physiology
Online Access:https://elifesciences.org/articles/69068

Internet

https://elifesciences.org/articles/69068

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