Age-Dependent Pre-Vaccination Immunity Affects the Immunogenicity of Varicella Zoster Vaccination in Middle-aged Adults

Age-Dependent Pre-Vaccination Immunity Affects the Immunogenicity of Varicella Zoster Vaccination in Middle-aged Adults

BackgroundPrevention of infectious diseases is of high priority in the rapidly aging population. Unfortunately, vaccine responses in the elderly are frequently diminished. Timely vaccination of middle-aged adults might improve the immune responses to vaccines, although knowledge on pathogen-specific...

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Bibliographic Details
Main Authors: Marieke van der Heiden, Lia G. H. de Rond, Menno C. van Zelm, Guy A. M. Berbers, Annemieke M. H. Boots, Anne-Marie Buisman
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
middle-aged adults
varicella zoster virus
T-cells
vaccination
cytokines
preexisting immunity
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00046/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00046/full

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