Intermittent Short-Term Infusion vs. Continuous Infusion of Piperacillin: Steady State Concentrations in Porcine Cervical Spine Tissue Evaluated by Microdialysis

Intermittent Short-Term Infusion vs. Continuous Infusion of Piperacillin: Steady State Concentrations in Porcine Cervical Spine Tissue Evaluated by Microdialysis

Background: Piperacillin is a central drug in the treatment of <i>Pseudomonas aeruginosa</i> spondylodiscitis. Intermittent short-term infusion (STI) remains standard treatment in most centres, although the application of continuous infusion (CI) has shown promising results in other clin...

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Bibliographic Details
Main Authors: Elisabeth Krogsgaard Petersen, Pelle Hanberg, Martin Knudsen, Sara Kousgaard Tøstesen, Andrea René Jørgensen, Kristina Öbrink-Hansen, Kjeld Søballe, Maiken Stilling, Mats Bue
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Antibiotics
Subjects:
piperacillin
spondylodiscitis
microdialysis
<i>Pseudomonas aeruginosa</i>
pharmacokinetics
Online Access:https://www.mdpi.com/2079-6382/11/7/910

Internet

https://www.mdpi.com/2079-6382/11/7/910

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