Dissecting the multifaceted contribution of the mitochondrial genome to autism spectrum disorder

Dissecting the multifaceted contribution of the mitochondrial genome to autism spectrum disorder

Autism spectrum disorder (ASD) is a clinically heterogeneous class of neurodevelopmental conditions with a strong, albeit complex, genetic basis. The genetic architecture of ASD includes different genetic models, from monogenic transmission at one end, to polygenic risk given by thousands of common...

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Bibliographic Details
Main Authors: Leonardo Caporali, Claudio Fiorini, Flavia Palombo, Martina Romagnoli, Flavia Baccari, Corrado Zenesini, Paola Visconti, Annio Posar, Maria Cristina Scaduto, Danara Ormanbekova, Agatino Battaglia, Raffaella Tancredi, Cinzia Cameli, Marta Viggiano, Anna Olivieri, Antonio Torroni, Elena Maestrini, Magali Jane Rochat, Elena Bacchelli, Valerio Carelli, Alessandra Maresca
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
mitochondrial DNA
mitochondrial haplogroups
universal heteroplasmy
autism spectrum disorder
autism risk
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.953762/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.953762/full

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