Loss of thyroid gland circadian PER2 rhythmicity in aged mice and its potential association with thyroid cancer development

Abstract Molecular clocks operate in peripheral tissues, including endocrine glands, and play important regulatory roles in this context. However, potential age-related changes in the expression rhythmicity of clock genes and the effects of these changes on the thyroid gland remain unknown. In the p...

Full description

Bibliographic Details
Main Authors: Junguee Lee, Hae Joung Sul, Hyunsu Choi, Dong Hyun Oh, Minho Shong
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05342-2