Loss of thyroid gland circadian PER2 rhythmicity in aged mice and its potential association with thyroid cancer development
Abstract Molecular clocks operate in peripheral tissues, including endocrine glands, and play important regulatory roles in this context. However, potential age-related changes in the expression rhythmicity of clock genes and the effects of these changes on the thyroid gland remain unknown. In the p...
Main Authors: | Junguee Lee, Hae Joung Sul, Hyunsu Choi, Dong Hyun Oh, Minho Shong |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-10-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-05342-2 |
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