Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways

Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways

Abstract Background Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and human papillomavirus (HPV) has been increasingly recognized as a pathogenic factor for the initiation and development of HNSCC. E6 oncogene, an essential component of the HPV 16 virus, act...

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Bibliographic Details
Main Authors: Yu Jin, Yuexiu Li, Xin Wang, Ya Yang
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Cancer Cell International
Subjects:
Head and neck squamous cell carcinoma
Human papillomavirus
Secretory leukocyte protease inhibitor
NF-κB
Akt pathway
Online Access:http://link.springer.com/article/10.1186/s12935-019-0942-7

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http://link.springer.com/article/10.1186/s12935-019-0942-7

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