Lipid-Nanoparticle-Mediated Delivery of Docetaxel Prodrug for Exploiting Full Potential of Gold Nanoparticles in the Treatment of Pancreatic Cancer

Lipid-Nanoparticle-Mediated Delivery of Docetaxel Prodrug for Exploiting Full Potential of Gold Nanoparticles in the Treatment of Pancreatic Cancer

Current chemoradiation therapy suffers from normal tissue toxicity. Thus, we are proposing incorporating gold nanoparticles (GNPs) and docetaxel (DTX), as they have shown very promising synergetic radiosensitization effects. Here, we explored the effect of a DTX prodrug encapsulated in lipid nanopar...

Full description

Bibliographic Details
Main Authors: Abdulaziz Alhussan, Nolan Jackson, Sarah Eaton, Nancy Dos Santos, Ingrid Barta, Josh Zaifman, Sam Chen, Yuen Yi C. Tam, Sunil Krishnan, Devika B. Chithrani
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
gold nanoparticles
docetaxel
lipid nanoparticles
pancreatic cancer
nanomedicine
Online Access:https://www.mdpi.com/2072-6694/14/24/6137

Internet

https://www.mdpi.com/2072-6694/14/24/6137

Similar Items